This Baked Cajun Salmon with Creamy Avocado Lime Sauce comes together in about 30 minutes and uses just a baking sheet for minimal cleanup, perfect for those busy weeknight dinners when you need something everyone will love! You can easily switch up the ingredients to suit your taste, and it’s a fantastic “clean out the fridge” meal if you have some extra veggies or grains lounging around.
Ingredients Breakdown
- Salmon Fillets
- Cajun Seasoning
- Olive Oil
- Avocado
- Lime
- Greek Yogurt
- Salt and Pepper
- Fresh Cilantro for Garnish
Let’s Get Cooking!
Preheat the Oven: First off, let crank that oven to 400°F (200°C). You want it hot enough to make that salmon sizzle.
Prepare the Salmon: Grab a good baking sheet and line it with parchment paper. Place the salmon fillets skin-side down, because who even has time for a dirty pan? Drizzle a little olive oil over each fillet, followed by an even sprinkle of Cajun seasoning on top.
Bake: Pop those beauties into the oven for about 12-15 minutes. You’ll know they’re done when they flake easily with a fork and have that lovely golden color trust me, the smell will be divine!
Make the Avocado Lime Sauce: While the salmon is baking, let’s whip up that sauce. In a blender, toss in the ripe avocado, squeeze in the lime juice, add the Greek yogurt, and sprinkle in some salt and pepper. Blend it all up until it’s smooth and creamy. If you want to get fancy, add a garlic clove for an extra kick!
Rest the Salmon: Once your timer goes off, take the salmon out of the oven and let it rest for a couple of minutes. This helps redistribute the juices, yum!
Serve and Garnish: Drizzle that creamy avocado lime sauce generously over the salmon, and don’t forget to top it with some fresh cilantro! It looks so pretty, your family’s going to want to dive in right away.

Why I Love This Recipe
This is my go-to recipe when I need something quick, tasty, and comforting. The best part is, it’s so versatile! I’m a real sucker for quick weeknight meals that don’t skimp on flavor, and this Baked Cajun Salmon delivers just that. Plus, it’s super easy to adjust with whatever you have on hand. Whether it’s the end of the week or just one of those busy nights, knowing I can throw this together is a lifesaver. Seriously, my picky 8-year-old even asked for seconds last time I made it!
If you loved this Baked Cajun Salmon with Creamy Avocado Lime Sauce, be sure to check out my Marry Me Salmon, my Salmon with Mango Salsa, or my Smoked Salmon Carbonara!
Why This Recipe Works
Quick & Easy
It really comes together in under 30 minutes, making it the perfect weeknight meal. You can make the sauce while the salmon is baking, talk about efficiency!
One-Pan Wonder
Since everything is done on one baking sheet, cleanup is a breeze. Simply toss the parchment paper, and you’re done!
Family-Friendly
The whole family will love it, and it’s sophisticated enough to impress guests. I mean, who doesn’t love beautifully cooked salmon dripping with creamy goodness?
Customizable
This recipe is super flexible! If you want to throw in some veggies, go for it. Broccoli, bell peppers, or even asparagus would be lovely roasted alongside the salmon.
Loaded with Flavor
With Cajun spices and that creamy avocado lime sauce, it’s bursting with flavor in every bite. I could eat this every night!
Serving Suggestions
This dish is delicious served with fluffy white rice, a refreshing salad, or even some quinoa for that extra crunch. You can also pair it with roasted veggies for a wholesome meal or serve it over a bed of leafy greens for a lighter option.
Storage: You can keep any leftovers in an airtight container in the fridge for up to 3 days. Just heat it gently in the microwave until warmed through.
Reheating Instructions: I recommend reheating it in the oven for the best texture. Just pop it in at 350°F (175°C) for about 10-15 minutes.
As for freezer-friendly? Unfortunately, while you can freeze cooked salmon, it’s best eaten fresh or with the creamy avocado lime sauce halved and stored separately.
Now,what are you waiting for? Grab those ingredients, and let’s get to cooking something delicious!
And just like that, you’re ready to serve up a fabulous dinner that’s sure to become a staple in your home. Enjoy this Baked Cajun Salmon with Creamy Avocado Lime Sauce, it’s a dish filled with warmth, love, and tons of flavor. Happy cooking, friends! Follow us on Pinterest for daily meal inspiration!

Baked Cajun Salmon with Creamy Avocado Lime Sauce
Ingredients
Method
- Preheat the oven to 400°F (200°C).
- Line a baking sheet with parchment paper and place the salmon fillets skin-side down.
- Drizzle olive oil over the salmon and sprinkle with Cajun seasoning.
- Bake the salmon for about 12-15 minutes, until it flakes easily with a fork and turns golden.
- In a blender, combine the ripe avocado, lime juice, Greek yogurt, and season with salt and pepper. Blend until smooth.
- Let the salmon rest for a couple of minutes after baking.
- Drizzle the creamy avocado lime sauce over the salmon and garnish with fresh cilantro.